نویسندگان
1 دانشگاه علوم پزشکی تهران
2 دانشگاه علوم پزشکی ایران
3 دانشگاه علوم پزشکی شهید بهشتی
4 وزارت بهداشت درمان و آموزش پزشکی
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Background: In recent years
platelet rich plasma (PRP) has been receiving growing attention in treatment of
soft –tissue injuries and lots of studies have been undertaken in many files
such as sport medicine and orthopedic surgery (treatment of chronic
tendinopathy), but there is limited well design randomize control trails in
this filed. To shed some light on these
controversies we conducted a systematic review and meta-analysis to determine
the efficacy of PRP on the improvement of physical function in
athletes.
Method: We searched Pub
Med, Cochrane Database of Systematic Reviews, DARE Database, Elsevier, EMBASE,
and Wiley Online Library for randomized controlled trials that studied on
application of PRP on athletes, sport medicine or orthopedic fields. Further,
we did additional searches by reference checking through the bibliographies of
eligible studies, contacting with authors, assessing grey literatures.
Results: The search retrieved 905 articles, from which 5 randomized control
trials met our inclusion criteria for systematic review and meta-analysis. The
quantitative analysis of physical activity/function, by VISA score (Victorian Institute of Sport Assessment) showed
that PRP is not more effective than other comparators.
Conclusions: These Meta-analyze prove no more effectiveness
for application of PRP in sport related injuries. Further well design RCTs are
needed to support these findings. According to lack of strong evidence to
support the effectiveness of PRP, increasing clinical use of platelet-rich
plasma for sport related injuries should be limited.
کلیدواژهها [English]
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